The shocking story of three generations of the Sackler family and their roles in the stories of Valium, OxyContin and the opioid crisis. The inspiration behind the Netflix series Painkiller, starring Uzo Aduba and Matthew Broderick.

Winner of the Baillie Gifford Prize for Non-Fiction
The Sunday Times Bestseller
A BBC Radio 4 ‘Book of the Week’
Shortlisted for the Financial Times/McKinsey Business Book of the Year Award
One of Barack Obama’s Favorite Books of the Year
Shortlisted for the Crime Writers’ Association Gold Dagger for Non-Fiction

‘I gobbled up Empire of Pain . . . a masterclass in compelling narrative nonfiction.’ – Elizabeth Day, The Guardian ’30 Best Summer Reads’

The Sackler name adorns the walls of many storied institutions like Harvard and the Metropolitan Museum of Art. They are one of the richest families in the world, known for their lavish donations in the arts and the sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing Oxycontin. A blockbuster painkiller that was a catalyst for the opioid crisis – an international epidemic of drug addiction which has killed nearly half a million people.

In this masterpiece of narrative reporting and writing, award-winning journalist and author of Say Nothing (now streaming on Disney+), Patrick Radden Keefe, exhaustively documents the jaw-dropping reality. Empire of Pain is the story of a dynasty, and twenty-first-century greed.

‘There are so many “they did what?” moments in this book, when your jaw practically hits the page’ – Sunday Times

‘You feel almost guilty for enjoying it so much’ – The Times

Hell Days

Hidden Heroes of Science

River of shadows

The secret lives of numbers

Empire of Pain